Category: Diseases!
- Cancer cachexia atlas links weight-loss episodes to clinical and genomic patterns ()
Published October 18, 2026. A Nature Medicine study published October 12 uses routine clinical records and tumor sequencing to map cancer-associated wasting over time. Researchers analyzed 52,236 patients treated at Memorial Sloan Kettering Cancer Center, with data spanning 2010–2024. The team identified 30,938 distinct episodes meeting consensus weight-loss criteria for cachexia, affecting 46.63% of the […]
- CONNECT trial supports glucose monitoring in type 2 diabetes without insulin ()
Published October 17, 2026. A randomized trial adds evidence that continuous glucose monitoring can improve blood-sugar control in adults with type 2 diabetes who do not use insulin. The CONNECT study was published in the New England Journal of Medicine on October 14, 2026. Researchers enrolled 283 adults at 22 U.S. primary-care practices and compared […]
- Restoring interneuron recruitment improves gamma rhythms in an Alzheimer’s mouse model ()
Published October 17, 2026. Researchers at UTHealth Houston and collaborating institutes report a way to improve disrupted brain rhythms in mice modelling features of Alzheimer’s disease. The findings appeared in Neuron on October 15, alongside a university announcement. The study focuses on parvalbumin interneurons, or PV cells, which help generate gamma oscillations associated with learning […]
- Tumour amino-acid metabolism reveals a route to suppressing T-cell activity ()
Published October 17, 2026. An October 16 Medical Xpress feature revisits research on how tumours alter amino-acid metabolism to support growth and weaken immune responses. The underlying study by Zhejiang University researchers appeared in Science Immunology on July 24, 2026. The team identified two complementary changes: increased SLC7A1 activity promoted arginine use and tumour growth, […]
- Brown fat and IL-6 link stress to arthritis flares in mice ()
Published October 17, 2026. Researchers at Chiba University and collaborating Japanese institutions have identified a biological pathway through which stress can reactivate joint inflammation in mice. The study appeared in Science Advances on October 16, 2026, with a university report dated October 17. In an arthritis model that had reached a remission-like state, restraint stress […]
- Genomic tracing reconstructs a rare cancer’s spread between twins before birth ()
Published October 17, 2026. A genomic investigation has reconstructed how a rare soft-tissue cancer began in one identical twin and crossed the placenta to the other before birth. The study appeared in Nature Communications on October 6, 2026, and received renewed coverage on October 16. Researchers from the Wellcome Sanger Institute, Great Ormond Street Hospital […]
- PPARD activation strengthens CAR T cells in preclinical tumor models ()
Published October 17, 2026. Cold Spring Harbor Laboratory researchers report that activating PPARδ, also called PPARD, in immune cells can strengthen their ability to attack tumors in experimental models. The work was published in Nature Immunology on October 14. PPARD regulates cellular metabolism, including fat use. Its effects depend on which cells activate it: the […]
- Adrabetadex: decade-long NPC observations presented in Montréal ()
Published October 17, 2026. Beren Therapeutics announced long-term observations for adrabetadex on October 15 at the Child Neurology Society meeting in Montréal. The experimental treatment targets disrupted cholesterol transport in infantile-onset Niemann-Pick disease type C, a rare neurodegenerative disorder. A case report followed two sisters receiving treatment for approximately a decade. According to the company, […]
- Bisphenol mixture alters human breast organoid development ()
Published October 16, 2026. Researchers at Tufts University and Boston University report that a mixture of three bisphenols altered the development of human breast organoids. The findings, described by Tufts on October 15 and published in PNAS, offer a laboratory approach to studying environmental exposures before disease develops. The team grew three-dimensional tissue models from […]
- Gamma delta T cells attack small cell lung cancer in laboratory models ()
Published October 16, 2026. WEHI researchers report that gamma delta T cells can recognize and attack small cell lung cancer in laboratory models. The institute described the Cancer Cell study on October 15. The team grew miniature tumors from patient samples and combined them with gamma delta T cells from the patients’ blood. These immune […]