Category: Nanomedicine
- Senescence-directed nanoparticles target fibrotic and immune-excluding tumor environments ()
Published October 26, 2026. A Nature Reviews Drug Discovery highlight published today draws attention to a September 24 Science study by Clemens Hinterleitner and colleagues on nanoparticles directed at disease-associated senescent-like cells. The researchers identified P-selectin on a subset of these cells in fibrotic tissues and tumors. They used fucoidan-based nanoparticles that bind P-selectin to […]
- Polypyrrole nanoparticles combine drug delivery and heating in prostate cancer cells ()
Published October 26, 2026. Fatemeh Imani and colleagues report a nanoparticle platform combining doxorubicin delivery with light-generated heating in prostate cancer cell cultures. Their study appeared October 26 in Scientific Reports as an early, accepted article that remains subject to editorial changes. The team investigated how oxidation defects in polypyrrole influence near-infrared absorption: more defects […]
- Icariin-loaded vesicles tested in retinal organoid injury models ()
Published October 26, 2026. A study published September 28 in Frontiers in Cell and Developmental Biology tested extracellular vesicles carrying icariin in laboratory models of retinal injury. Mira Park and colleagues used R28 retinal progenitor cells and retinal organoids derived from human embryonic stem cells. The researchers exposed these models to cobalt chloride, a chemical […]
- Piezoelectric Biomaterials Review Links Biofilm Control and Infected Bone Repair ()
Published October 26, 2026. A mini-review published October 16 in Frontiers in Cell and Developmental Biology examines piezoelectric biomaterials for infected bone repair. Zhen Wang and colleagues discuss materials that convert mechanical stimulation, including ultrasound or movement, into localized electrical signals. In some systems, the resulting electrical activity can also promote reactive oxygen species that […]
- Nanotechnology Review Connects Cryoprotectant Delivery, Ice Control and Rewarming ()
Published October 26, 2026. A review published online October 15 in Tissue and Cell examines how nanotechnology could address several sources of cryopreservation injury. Juhyun Kim, Yeonwoo Jang and Hansoo Park discuss strategies spanning individual cells and three-dimensional structures such as spheroids and organoids. Freezing and thawing can damage biological material through ice formation, osmotic […]
- Rg3 Liposomes Show Protective Effects in Experimental Parkinson’s Models ()
Published October 26, 2026. Liposomes carrying ginsenoside Rg3 showed protective effects in experimental Parkinson’s disease models, according to a study published October 21 in Frontiers in Cell and Developmental Biology. Xiaohan Zhang and colleagues tested the formulation in toxin-exposed SH-SY5Y cells and mice given MPTP. The optimized particles averaged about 171 nanometers. In cell experiments, […]
- TPT Nanomicelles Reduce Retinal Inflammation in a Mouse Uveitis Model ()
Published October 26, 2026. An experimental nanomaterial reduced retinal inflammation in mice with autoimmune uveitis, according to research published October 23 in the Journal of Translational Medicine. Chao Wu and colleagues investigated TPT nanomicelles, abbreviated TPTN, through laboratory experiments and a mouse disease model. The material scavenged reactive oxygen species and showed low cytotoxicity under […]
- Lung Nanomedicine: Review Examines Delivery Barriers and Clinical Translation ()
Published October 26, 2026. A review published September 1 in Signal Transduction and Targeted Therapy examines how nanomedicines could deliver treatments more precisely to diseased lung tissues. Zicheng Deng and colleagues compare delivery strategies across conditions including pulmonary fibrosis, infections and lung cancer. The central challenge is getting a therapeutic payload to the right cells. […]
- Smaller cellular nanodiscs improve toxin neutralization in preclinical experiments ()
Published October 26, 2026. An October 20 research update from UC San Diego highlights how particle size affects cellular nanodiscs, drawing attention to a study first published in Small on March 24, 2026. Kailin Feng and colleagues combined laboratory experiments with Brownian dynamics simulations to compare red-blood-cell-membrane nanodiscs measuring approximately 71, 26 and 15 nanometers. […]
- Eggshell-membrane zinc oxide nanohybrid studied for sperm cryopreservation ()
Published October 25, 2026. A study released on October 6 in Advanced Composites and Hybrid Materials explores an eggshell-membrane scaffold carrying zinc oxide nanostructures for experimental sperm preservation. Researchers compared nanocomposites produced through chemical, thermal and biogenic routes. The thermally prepared formulation showed the strongest overall performance in the reported laboratory tests, including stability, sustained […]